Posts by: Joana Carvalho

Joana Carvalho

Joana holds a BSc in Biology, a MSc in Evolutionary and Developmental Biology and a PhD in Biomedical Sciences from Universidade de Lisboa, Portugal. Her work has been focused on the impact of non-canonical Wnt signaling in the collective behavior of endothelial cells — cells that made up the lining of blood vessels — found in the umbilical cord of newborns.

January 7, 2021January 7, 2021

FDA Approves Generic of Banzel as Add-on Seizure Therapy

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The U.S. Food and Drug Administration (FDA) has approved Lupin Limited’s generic medication, Rufinamide Oral Suspension, to be used as an add-on therapy to control seizures in adults and children, ... Read more

December 17, 2020December 17, 2020

Fintepla Found to Safely Reduce LGS Seizure Frequency

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Fintepla (fenfluramine) safely lowered the frequency of drop seizures — those where part or all of the body may become limp — in patients with Lennox-Gastaut syndrome (LGS), according to ... Read more

December 3, 2020December 3, 2020

Epidiolex’s Anti-Seizure Activity Not Affected by Clobazam, Review Study Finds

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When given as an add-on therapy, Epidiolex (cannabidiol, CBD) can lower the frequency of seizures in young patients with Dravet and Lennox‐Gastaut syndromes — regardless of whether the children also ... Read more

September 17, 2020September 17, 2020

Epidiolex-Valproic Acid Combo Can Lower Platelet Counts in Children With LGS, Study Finds

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When used alongside valproic acid, Epidiolex (cannabidiol) can increase the risk of thrombocytopenia in children and adolescents with drug-resistant forms of epilepsy, such as Lennox-Gastaut syndrome (LGS), a study shows. According ... Read more

September 10, 2020September 10, 2020

Soticlestat Safely Lowered Seizure Frequency in Children With LGS, Top-line Data Show

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Treatment with soticlestat (OV935/TAK-935) safely led to a clinically meaningful reduction in the frequency of hard-to-treat seizures in a group of children with Dravet and Lennox-Gastaut (LGS) syndromes, according to top-line ... Read more

July 23, 2020July 23, 2020

Cannabidiol Epidiolex Can Increase Diacomit Levels in Epilepsy Patients, Study Finds

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Using the cannabidiol Epidiolex in combination with Diacomit (stiripentol) or Depacon (sodium valproate) — two anti-epileptic treatments — does not seem to raise major safety concerns among patients with seizures ... Read more

May 7, 2020May 7, 2020

Epidiolex Safely Lowers Seizure Frequency in Children, 3-Year Study Data Show

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When used alongside other anti-epileptic medications, Epidiolex (cannabidiol, CBD) safely reduces the frequency of seizures in children with Lennox-Gastaut syndrome (LGS), according to three-year data from a long-term extension study. ... Read more

April 16, 2020April 16, 2020

ET-101 Is Biologically Equivalent to Approved Topiramate Solid Products, Study Shows

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ET-101, Eton Pharmaceuticals’ proprietary topiramate oral solution shows similar properties and is biologically equivalent to the currently approved topiramate oral solid product, according to data from a bioequivalence study conducted ... Read more

January 9, 2020January 9, 2020

People With Late-Onset LGS May Maintain Their Cognitive and Functional Abilities, Study Finds

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People who start showing signs of Lennox-Gastaut syndrome later in life seem to be able to maintain their cognitive and functional abilities, a study has found. The results of the ... Read more