International Epilepsy Day (IED), falling on Feb. 8 this year, calls attention to the needs of the roughly 50 million people globally who are affected by the brain disorder. “This is a day for everyone, no matter where you are, no matter how small your group or large your area,…
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Jazz Pharmaceuticals announced the signing of a definitive agreement for it to acquire GW Pharmaceuticals and holdings that include Epidiolex, an approved oral cannabinoid treatment for seizures in Lennox-Gastaut syndrome (LGS) patients. “We are excited to add GW’s industry-leading cannabinoid platform, innovative pipeline and products, which will strengthen and broaden…
Cannabidiol (CBD) — the active ingredient in Epidiolex — was found to bind to and block the opening of the sodium channel protein associated with seizures in people with Lennox-Gastaut syndrome (LGS), a study has shown. The findings describe the…
Telehealth visits — conferencing with patients via video or phone calls — are generally viewed favorably by both the treating physicians and the parents of children with epileptic conditions like Lennox-Gastaut syndrome (LGS), a French study reports. The study, “Usefulness, limitations, and parental opinion about teleconsultation…
The U.S. Food and Drug Administration (FDA) has approved Lupin Limited’s generic medication, Rufinamide Oral Suspension, to be used as an add-on therapy to control seizures in adults and children, ages 1 and older, with Lennox-Gastaut syndrome (LGS), according to a press release. Rufinamide is a generic version…
Fintepla (fenfluramine) safely lowered the frequency of drop seizures — those where part or all of the body may become limp — in patients with Lennox-Gastaut syndrome (LGS), according to data from a Phase 3 trial. The study (NCT03355209) also showed the medication was able to lower…
Researchers have developed a new “hard-stop alert” that pops up when clinicians are trying to prescribe carbohydrate-containing medications to hospitalized children on a keto diet — a ketogenic eating plan that is high-fat and low-carb. Notably, this type of diet is recommended for patients with treatment-resistant epilepsy, such as…
When given as an add-on therapy, Epidiolex (cannabidiol, CBD) can lower the frequency of seizures in young patients with Dravet and Lennox‐Gastaut syndromes — regardless of whether the children also are taking clobazam — a review has found. These findings suggest that Epidiolex may have…
Adding Epidiolex, an oral cannabidiol medication, to other treatments successfully stopped epileptic seizures in a boy with Lennox-Gastaut syndrome (LGS), resulting in nearly normal electrical activity in the brain, a real-world case study reported. The case study, “…
National Epilepsy Awareness Month is underway, with a variety of events and activities aimed at calling attention to diseases such as Dravet and Lennox-Gastaut syndromes, and to epilepsy in general. Patients, caregivers, and advocates around the U.S. will share educational information, host fundraisers, don purple gear,…
Recent
- Taking Time to Acknowledge Our Efforts as Parents and Caregivers
- Eurordis Survey: Healthcare Experience Worse for Rare Disease Patients
- Brian Is a Happy Little Man
- Pandemic Won’t Stop Rare Disease Day on Feb. 28
- I’m Ready to Embrace My Emotions as an LGS Caregiver
- International Epilepsy Day Shines Spotlight on Brain Disorder Affecting Millions
- NORD’s 6th ‘State Report Card’ Notes Progress, Raises Concerns
- Jazz Acquires GW Pharma and Epidiolex, Other Potential Cannabinoids
- Study Reveals Molecular Details of Epidiolex Action
- This Is Why I Had to Sign Off