Two nerve-stimulating devices, vagus nerve stimulation (VNS) and deep brain stimulation (DBS), were associated with similar reductions in seizure frequency over two years in people with Lennox-Gastaut syndrome (LGS), according to a Mayo Clinic…
Latest News
The initial results from a large, late-stage clinical trial testing an oral seizure treatment for people with Lennox-Gastaut syndrome (LGS) and other epileptic conditions are expected by the end of this year or early…
Carisbamate, an experimental oral therapy for the treatment of seizures in people with Lennox-Gastaut syndrome (LGS), was generally safe and well-tolerated in children, adolescents, and adults with the disease, according to data from…
A new mouse model of Lennox-Gastaut syndrome (LGS) accurately reproduced key features of the disease and responded to approved and investigational therapies, providing the first pharmacological validation of the model, a new study reports.
A girl with difficult-to-treat CDKL5 deficiency disorder (CDD), whose epilepsy later developed into Lennox–Gastaut syndrome (LGS), became seizure-free for more than 11 months after treatment with low-dose Fintepla (fenfluramine), suggesting this medication may be…
The Lennox-Gastaut Syndrome (LGS) Foundation has launched a collaborative research accelerator to unite experts, dismantle research roadblocks, and speed up the development of new treatments for LGS and related developmental and epileptic encephalopathies (DEEs).
Community Perspectives
Although my 11-year-old son, little Brian, has Lennox-Gastaut syndrome and is nonverbal, he lives and behaves like a royal prince. His home is his kingdom, and with me as his personal bodyguard, we march…
As I sit in rush-hour traffic, a hot Florida sun beams brightly through my windshield. Drivers around me jostle for position, frantically trying to shave off a few seconds of commute time. A cacophony of…
As humans, and especially as caregivers, we do not give ourselves enough credit. It’s a widely accepted expectation that we should always strive to do better. I don’t necessarily disagree with that sentiment, as…
Little Brian is awesome. As I take this time to reflect on the totality of the life that currently exists for me, I struggle to maintain a positive outlook. Lennox-Gastaut syndrome (LGS) has completely upended…
No matter how cliché it sounds, if there’s anything I can get across as a Lennox-Gastaut syndrome (LGS) caregiver, it’s that the experience is truly an emotional roller coaster. At the time of writing my…
It’s good to be back and writing again. My last column was posted over a month ago, before the winter holidays. I wish I could say the entirety of my time away was spent in…
